There are many opportunities to view wildlife such as white-tailed deer, beaver, raccoon, fox and porcupine. The park is also home to such turtle species as the painted turtle and spotted turtle, numerous snakes and amphibians. More than 200 species of birds have been sighted here, including the black-crowned night heron and the American egret which find the wetlands in the park to be ideal feeding grounds. The shoreline is a recognized spring and fall migration route. MacGregor Point is either the northern or southern nesting limit for a number of northern and southern species.

Each spring naturalists' celebrate the return of songbirds during the Huron Fringe Birding Festival. This festival has been developed to coincide with the arrival and the setting up of territories by these migrating birds. The focus is on birding, however, other areas of natural history are included such as butterflies, wildflowers, astronomy, nature art, poetry and photography. The festival is held annually for ten days from the Friday following the Victoria Day weekend.

The park is well known for its diverse wetland environments. They are home to many common wildflowers as well as to such interesting plants as the carnivorous pitcher-plant and sundew. The Lake Huron shoreline is ideal habitat for the dwarf lake iris which is found in isolated locations in Ontario.